Keratoacanthoma

Keratoacanthoma, also known as well-differentiated squamous cell carcinoma, is related to muir-torre syndrome and vulva squamous cell carcinoma, and has symptoms including exanthema and pruritus. An important gene associated with Keratoacanthoma is NOTCH1 (Notch Receptor 1), and among its related pathways/superpathways are Infectious disease and ERK Signaling. The drugs Lidocaine and Anesthetics have been mentioned in the context of this disorder. Affiliated tissues include skin and tongue, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased cell migration