Keratoconjunctivitis Sicca, also known as dry eye syndromes, is related to aplasia of lacrimal and salivary glands and sjogren syndrome, and has symptoms including dryness of eye, eye manifestations and dacryops. An important gene associated with Keratoconjunctivitis Sicca is LTF (Lactotransferrin), and among its related pathways/superpathways are Innate Immune System and MIF Mediated Glucocorticoid Regulation. The drugs Benzocaine and Dipivefrin have been mentioned in the context of this disorder. Affiliated tissues include eye and salivary gland, and related phenotypes are homeostasis/metabolism and cellular