Klippel-Trenaunay-Weber Syndrome (KTS)

Klippel-Trenaunay-Weber Syndrome, also known as klippel-trenaunay syndrome, is related to weber syndrome and hemangioma. An important gene associated with Klippel-Trenaunay-Weber Syndrome is PIK3CA (Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha), and among its related pathways/superpathways are ERK Signaling and Signal Transduction. The drugs Temsirolimus and Sirolimus have been mentioned in the context of this disorder. Affiliated tissues include bone and skin, and related phenotypes are hemangioma and venous insufficiency