Kleine-Levin Hibernation Syndrome

Kleine-Levin Hibernation Syndrome, also known as kleine-levin syndrome, is related to hypersomnia and idiopathic hypersomnia. An important gene associated with Kleine-Levin Hibernation Syndrome is TRANK1 (Tetratricopeptide Repeat And Ankyrin Repeat Containing 1), and among its related pathways/superpathways is Orexin and neuropeptides FF and QRFP bind to their respective receptors. The drugs Technetium Tc 99m bicisate and Radiopharmaceuticals have been mentioned in the context of this disorder. Affiliated tissues include thalamus and hypothalamus, and related phenotypes are cognitive impairment and confusion