Juvenile Amyotrophic Lateral Sclerosis, also known as juvenile lou gehrig disease, is related to amyotrophic lateral sclerosis 4, juvenile and lateral sclerosis. An important gene associated with Juvenile Amyotrophic Lateral Sclerosis is ALS2 (Alsin Rho Guanine Nucleotide Exchange Factor ALS2). Affiliated tissues include skeletal muscle and cerebellum, and related phenotypes are muscle weakness and skeletal muscle atrophy