Juvenile Absence Epilepsy (JAE)

Juvenile Absence Epilepsy, also known as jae, is related to focal epilepsy and epilepsy, idiopathic generalized, and has symptoms including seizures, absence attacks and absence seizures. An important gene associated with Juvenile Absence Epilepsy is EFHC1 (EF-Hand Domain Containing 1), and among its related pathways/superpathways are Activation of cAMP-Dependent PKA and CREB Pathway. The drugs Ethosuximide and Lamotrigine have been mentioned in the context of this disorder. Affiliated tissues include brain and eye, and related phenotypes are bilateral tonic-clonic seizure and generalized-onset seizure