Intellectual Developmental Disorder with Microcephaly and Pontine and Cerebellar Hypoplasia (MICPCH)

Intellectual Developmental Disorder with Microcephaly and Pontine and Cerebellar Hypoplasia, also known as mental retardation and microcephaly with pontine and cerebellar hypoplasia, is related to syndromic x-linked intellectual disability najm type and cask-related disorders, and has symptoms including muscle spasticity and muscle weakness. An important gene associated with Intellectual Developmental Disorder with Microcephaly and Pontine and Cerebellar Hypoplasia is CASK (Calcium/Calmodulin Dependent Serine Protein Kinase), and among its related pathways/superpathways is Olfactory Signaling Pathway. Affiliated tissues include eye and brain, and related phenotypes are intellectual disability, moderate and severe global developmental delay