Integumentary System Disease is related to nail disease and hair disease. An important gene associated with Integumentary System Disease is CBS (Cystathionine Beta-Synthase), and among its related pathways/superpathways are MIF Mediated Glucocorticoid Regulation and TGF-Beta Pathway. Affiliated tissues include skin and integumentary system comprising the skin, and related phenotypes are immune system and endocrine/exocrine gland