Intracranial Hypertension, also known as raised intracranial pressure, is related to papilledema and hypertension, essential, and has symptoms including headache, vomiting and altered mental status. An important gene associated with Intracranial Hypertension is F3 (Coagulation Factor III, Tissue Factor), and among its related pathways/superpathways are Interleukin-4 and Interleukin-13 signaling and Neuroinflammation and glutamatergic signaling. The drugs Lymecycline and Doxycycline have been mentioned in the context of this disorder. Affiliated tissues include brain and liver, and related phenotypes are nervous system and homeostasis/metabolism