Internuclear Ophthalmoplegia

Alias:
Mlf - [medial Longitudinal Fasciculus] Syndrome
Ino - [internuclear Ophthalmoplegia]
Bielschowsky-Lutz-Cogan Syndrome
Ophthalmoplegia Internuclearis
Internuclear Paralysis
Lhermitte Syndrome
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Internuclear Ophthalmoplegia, also known as mlf - [medial longitudinal fasciculus] syndrome, is related to facial paralysis and myasthenia gravis, and has symptoms including ophthalmoplegia, spasm of conjugate gaze and anomalies of divergence. An important gene associated with Internuclear Ophthalmoplegia is MOG (Myelin Oligodendrocyte Glycoprotein), and among its related pathways/superpathways are ECM proteoglycans and 1p36 copy number variation syndrome. The drugs Dalfampridine and Histamine have been mentioned in the context of this disorder. Affiliated tissues include eye and pons, and related phenotypes are nervous system and muscle
Related ID:
MESH:D015835
ICD11:377040542

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
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Unknown
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13
141
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Medical Symptom

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Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

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No data available

Related Drugs

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No data available

Disease Model

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Name
MGI
Related Gene
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Publications
No data available

References Literature

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IF
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