Intermittent Explosive Disorder

Intermittent Explosive Disorder, also known as explosive personality disorder, is related to pyromania and avoidant personality disorder. An important gene associated with Intermittent Explosive Disorder is SLC6A4 (Solute Carrier Family 6 Member 4), and among its related pathways/superpathways are Sudden infant death syndrome (SIDS) susceptibility pathways and Monoamine GPCRs. The drugs Guanfacine and Naratriptan have been mentioned in the context of this disorder. Affiliated tissues include temporal lobe and amygdala.