Intracranial Hypotension is related to thrombosis and abducens palsy. An important gene associated with Intracranial Hypotension is PTGDS (Prostaglandin D2 Synthase), and among its related pathways/superpathways are Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) and Angiotensin II receptor type 1 pathway. The drugs Acetazolamide and Acetylsalicylic acid have been mentioned in the context of this disorder. Affiliated tissues include brain and spinal cord, and related phenotype is nervous system.