Insensitivity to Pain, Congenital, with Anhidrosis (CIPA)

Insensitivity to Pain, Congenital, with Anhidrosis, also known as congenital insensitivity to pain with anhidrosis, is related to neuropathy, hereditary sensory and autonomic, type v and hereditary sensory neuropathy. An important gene associated with Insensitivity to Pain, Congenital, with Anhidrosis is NTRK1 (Neurotrophic Receptor Tyrosine Kinase 1), and among its related pathways/superpathways are Pleural mesothelioma and Signaling by NTRKs. The drugs Verapamil and Ritonavir have been mentioned in the context of this disorder. Affiliated tissues include bone and tongue, and related phenotypes are intellectual disability and abnormality of peripheral nerve conduction