Inclusion Body Myopathy with Early-Onset Paget Disease of Bone with or Without Frontotemporal Dementia 2 (MSP2)

Inclusion Body Myopathy with Early-Onset Paget Disease of Bone with or Without Frontotemporal Dementia 2, also known as multisystem proteinopathy 2, is related to inclusion body myopathy with early-onset paget disease with or without frontotemporal dementia 2 and malaria. An important gene associated with Inclusion Body Myopathy with Early-Onset Paget Disease of Bone with or Without Frontotemporal Dementia 2 is LDB3 (LIM Domain Binding 3), and among its related pathways/superpathways is Involvement of -secretase in neurodegenerative diseases. Affiliated tissues include bone and placenta, and related phenotypes are Increased SMN2 exon 7 inclusion and homeostasis/metabolism