Inclusion Body Myositis (IBM)

Inclusion Body Myositis, also known as sporadic inclusion body myositis, is related to myositis and myopathy, and has symptoms including back pain, muscle cramp and muscle rigidity. An important gene associated with Inclusion Body Myositis is GNE (Glucosamine (UDP-N-Acetyl)-2-Epimerase/N-Acetylmannosamine Kinase), and among its related pathways/superpathways are Neuroscience and miRNA role in immune response in sepsis. The drugs Titanium dioxide and Silicon have been mentioned in the context of this disorder. Affiliated tissues include skeletal muscle and bone, and related phenotypes are skeletal muscle atrophy and autoimmunity