Impotence, also known as erectile dysfunction, is related to vasculogenic impotence and apnea, obstructive sleep, and has symptoms including angina pectoris, pelvic pain and tremor. An important gene associated with Impotence is PDE5A (Phosphodiesterase 5A), and among its related pathways/superpathways are Signal Transduction and Response to elevated platelet cytosolic Ca2+. The drugs Benzocaine and Nebivolol have been mentioned in the context of this disorder. Affiliated tissues include bone marrow and prostate, and related phenotypes are homeostasis/metabolism and nervous system