Immunodeficiency 8 with Lymphoproliferation, also known as severe combined immunodeficiency due to coro1a deficiency, is related to immunodeficiency, common variable, 8, with autoimmunity and autoimmune disease. An important gene associated with Immunodeficiency 8 with Lymphoproliferation is CORO1A (Coronin 1A). Affiliated tissues include t cells and thymus, and related phenotypes are gastroesophageal reflux and immunodeficiency