Immune Dysregulation with Autoimmunity, Immunodeficiency, and Lymphoproliferation (IDAIL)

Alias:
Autoimmune Lymphoproliferative Syndrome Due to Ctla4 Haploinsuffiency
Autoimmune Lymphoproliferative Syndrome, Type V
Chai
Ctla-4 Haploinsufficiency with Autoimmune Infiltration Disease
Alps Due to Ctla4 Haploinsuffiency
Idail
Alps5
Ctla4 Haploinsufficiency with Autoimmune Infiltration
Autoimmune Lymphoproliferative Syndrome Type V
Autoimmune Lymphoproliferative Syndrome 5
Lymphoproliferative Disorders
Favorite
Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Immune Dysregulation with Autoimmunity, Immunodeficiency, and Lymphoproliferation, also known as autoimmune lymphoproliferative syndrome due to ctla4 haploinsuffiency, is related to pontocerebellar hypoplasia, type 14 and pontocerebellar hypoplasia, type 15, and has symptoms including diarrhea An important gene associated with Immune Dysregulation with Autoimmunity, Immunodeficiency, and Lymphoproliferation is CTLA4 (Cytotoxic T-Lymphocyte Associated Protein 4). The drugs Tacrolimus and Basiliximab have been mentioned in the context of this disorder. Affiliated tissues include t cells and bone marrow, and related phenotypes are decreased circulating antibody level and splenomegaly
Related ID:

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
AD
Child
<1/1000000
1
11
27

Medical Symptom

#
Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

#
Gene
Function
Score
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
No data available

Disease Model

Category
Name
MGI
Related Gene
Strain of Origin
Publications
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Comparison
Al agent
Tutorials
Back to top