Immunoglobulin Heavy Chain Amyloidosis

Alias:
Heavy Chain Amyloidosis
Ah Amyloidosis
Amyloidosis Derived from Immunoglobulin Heavy Chain
Ig Heavy-Chain-Associated Amyloidosis
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Immunoglobulin Heavy Chain Amyloidosis, also known as heavy chain amyloidosis, is related to immunoglobulin heavy-and-light chain and lattice corneal dystrophy. An important gene associated with Immunoglobulin Heavy Chain Amyloidosis is DNAJB9 (DnaJ Heat Shock Protein Family (Hsp40) Member B9), and among its related pathways/superpathways are Ebola virus infection in host and Ca, cAMP and Lipid Signaling. The drugs Temsirolimus and Benzocaine have been mentioned in the context of this disorder. Affiliated tissues include liver and bone.
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Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
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Newborn
<1/1000000
7
29
--

Medical Symptom

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Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

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Gene
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Score
Mutations
No data available

Related Drugs

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CAS Number
Status
Phase
No data available

Disease Model

Category
Name
MGI
Related Gene
Strain of Origin
Publications
No data available

References Literature

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PMID
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IF
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