Immunoglobulin Light Chain Amyloidosis

Alias:
Primary Amyloidosis
Al Amyloidosis
Primary Systemic Amyloidosis
Light-Chain Amyloidosis
Hereditary Amyloid Nephropathy Due to Lysozyme Variant
Familial Amyloid Nephropathy Due to Lysozyme Variant
Hereditary Renal Amyloidosis Due to Lysozyme Variant
Familial Renal Amyloidosis Due to Lysozyme Variant
Immunoglobulin Light-Chain Amyloidosis
Immunoglobulin Deposition Disease
Primary Systemic Al Amyloidosis
Amyloidosis Primary Systemic
Immunoglobulinic Amyloidosis
Light Chain Amyloidosis
Systemic Al Amyloidosis
Primary Al Amyloidosis
Systemic Al Amyloidsis
Lysozyme Amyloidosis
Amyloidosis Primary
Alys Amyloidosis
Amyloid Al
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Immunoglobulin Light Chain Amyloidosis, also known as primary amyloidosis, is related to primary cutaneous amyloidosis and myeloma, multiple. An important gene associated with Immunoglobulin Light Chain Amyloidosis is LYZ (Lysozyme), and among its related pathways/superpathways are Binding and Uptake of Ligands by Scavenger Receptors and Ca, cAMP and Lipid Signaling. The drugs Ichthammol and Daratumumab have been mentioned in the context of this disorder. Affiliated tissues include liver and spleen, and related phenotypes are fatigue and proteinuria
Related ID:
MESH:D000075363
ICD11:1061366491

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
AD
Unknown
1-5/10000
21
164
--

Medical Symptom

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Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

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Related Drugs

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Disease Model

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MGI
Related Gene
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Publications
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References Literature

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IF
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