Immunodeficiency 60, also known as bach2-related immunodeficiency and autoimmunity, is related to immunodeficiency 60 and autoimmunity and immunodeficiency 58. An important gene associated with Immunodeficiency 60 is BACH2 (BTB Domain And CNC Homolog 2), and among its related pathways/superpathways is Extrafollicular and follicular B cell activation by SARS-CoV-2. Affiliated tissues include b cells and liver, and related phenotypes are chronic diarrhea and recurrent sinopulmonary infections