Immunoglobulin a Deficiency 1, also known as immunoglobulin a deficiency, is related to agammaglobulinemia and systemic scleroderma. An important gene associated with Immunoglobulin a Deficiency 1 is IGAD1 (Immunoglobulin A (IgA) Deficiency Susceptibility 1), and among its related pathways/superpathways are Innate Immune System and Akt Signaling. The drug Immunoglobulin A has been mentioned in the context of this disorder. Affiliated tissues include small intestine and b cells, and related phenotypes are recurrent respiratory infections and malabsorption