Immunodeficiency 11a (IMD11A)

Immunodeficiency 11a, also known as severe combined immunodeficiency due to card11 deficiency, is related to b-cell expansion with nfkb and t-cell anergy and omenn syndrome. An important gene associated with Immunodeficiency 11a is CARD11 (Caspase Recruitment Domain Family Member 11), and among its related pathways/superpathways are Innate Immune System and TCR Signaling (Qiagen). Affiliated tissues include b cells and t cells, and related phenotypes are recurrent respiratory infections and immunodeficiency