Immune System Disease, also known as abnormality of the immune system, is related to lymphatic system disease and immune deficiency disease, and has symptoms including pathological conditions, signs and symptoms An important gene associated with Immune System Disease is PIK3CD (Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Delta), and among its related pathways/superpathways are MicroRNAs in cardiomyocyte hypertrophy and miRNA role in immune response in sepsis. The drugs Midazolam and Morphine have been mentioned in the context of this disorder. Affiliated tissues include t cells and bone marrow.