Immunoglobulin Kappa Light Chain Deficiency (IGKCD)

Immunoglobulin Kappa Light Chain Deficiency, also known as recurrent infections associated with rare immunoglobulin isotypes deficiency, is related to hyper-ige syndrome 1, autosomal dominant, with recurrent infections and systemic lupus erythematosus. An important gene associated with Immunoglobulin Kappa Light Chain Deficiency is IGKC (Immunoglobulin Kappa Constant), and among its related pathways/superpathways are Development Angiotensin activation of ERK and Immune response NFAT in immune response. Affiliated tissues include liver and skin, and related phenotypes are recurrent respiratory infections and recurrent upper respiratory tract infections