Immunodeficiency, Common Variable, 1 (CVID1)

Immunodeficiency, Common Variable, 1, also known as antibody deficiency due to icos defect, is related to immunodeficiency with hyper-igm, type 1 and common variable immunodeficiency, and has symptoms including diarrhea An important gene associated with Immunodeficiency, Common Variable, 1 is ICOS (Inducible T Cell Costimulator), and among its related pathways/superpathways are Innate Immune System and Immune response NFAT in immune response. Affiliated tissues include b cells and t cells, and related phenotypes are neutropenia in presence of anti-neutropil antibodies and decreased circulating iga level