Ileus, also known as ileus of intestine, is related to paralytic ileus and intestinal obstruction. An important gene associated with Ileus is GUCY2C (Guanylate Cyclase 2C), and among its related pathways/superpathways are Innate Immune System and MIF Mediated Glucocorticoid Regulation. The drugs Lidocaine and Gabapentin have been mentioned in the context of this disorder. Affiliated tissues include colon and small intestine, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and homeostasis/metabolism