Ichthyosis, Leukocyte Vacuoles, Alopecia, and Sclerosing Cholangitis (ILVASC)

Ichthyosis, Leukocyte Vacuoles, Alopecia, and Sclerosing Cholangitis, also known as neonatal ichthyosis-sclerosing cholangitis syndrome, is related to ichthyosis and hypertension, essential, and has symptoms including icterus An important gene associated with Ichthyosis, Leukocyte Vacuoles, Alopecia, and Sclerosing Cholangitis is CLDN1 (Claudin 1), and among its related pathways/superpathways are Integrin Pathway and Sertoli-Sertoli Cell Junction Dynamics. Affiliated tissues include skin and liver, and related phenotypes are splenomegaly and hepatomegaly