Hyper-Ige Syndrome 4a, Autosomal Dominant, with Recurrent Infections, is also known as hyper-ige recurrent infection syndrome 4a, autosomal dominant. An important gene associated with Hyper-Ige Syndrome 4a, Autosomal Dominant, with Recurrent Infections is IL6ST (Interleukin 6 Cytokine Family Signal Transducer). Affiliated tissues include t cells and bone, and related phenotypes are increased circulating ige level and recurrent pneumonia