Hyper Ige Recurrent Infection Syndrome 1

Hyper Ige Recurrent Infection Syndrome 1, also known as job syndrome, is related to combined immunodeficiency due to dock8 deficiency and trichosporonosis. An important gene associated with Hyper Ige Recurrent Infection Syndrome 1 is STAT3 (Signal Transducer And Activator Of Transcription 3), and among its related pathways/superpathways are Infectious disease and Innate Immune System. The drugs Posaconazole and Cytochrome P-450 Enzyme Inhibitors have been mentioned in the context of this disorder. Affiliated tissues include bone marrow and lung, and related phenotypes are homeostasis/metabolism and growth/size/body region