Hypercholesterolemia, Familial, 2 (FHCL2)

Hypercholesterolemia, Familial, 2, also known as hypercholesterolemia, autosomal dominant, type b, is related to hypobetalipoproteinemia, familial, 1 and hyperlipidemia, familial combined, 3. An important gene associated with Hypercholesterolemia, Familial, 2 is APOB (Apolipoprotein B), and among its related pathways/superpathways are Vesicle-mediated transport and Metabolism of water-soluble vitamins and cofactors. The drugs Hypolipidemic Agents and Lipid Regulating Agents have been mentioned in the context of this disorder. Affiliated tissues include heart, and related phenotypes are increased ldl cholesterol concentration and hypercholesterolemia