Hypertension, Essential, also known as essential hypertension, is related to pulmonary hypertension and renovascular hypertension, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Hypertension, Essential is AGTR1 (Angiotensin II Receptor Type 1), and among its related pathways/superpathways are Development Angiotensin activation of ERK and Corticotropin-releasing hormone signaling pathway. The drugs Canrenoic acid and Cisatracurium have been mentioned in the context of this disorder. Affiliated tissues include heart and kidney, and related phenotypes are elevated systolic blood pressure and elevated diastolic blood pressure