Hypoganglionosis

Hypoganglionosis is related to hirschsprung disease 1 and visceral neuropathy, familial, 1, autosomal recessive. An important gene associated with Hypoganglionosis is ERBB2 (Erb-B2 Receptor Tyrosine Kinase 2), and among its related pathways/superpathways are Actin Nucleation by ARP-WASP Complex and NFAT and Cardiac Hypertrophy. Affiliated tissues include colon and small intestine, and related phenotypes are Decreased viability and Increased shRNA abundance (Z-score > 2)