Hyperaldosteronism, Familial, Type Iii, also known as familial hyperaldosteronism type iii, is related to familial hyperaldosteronism and hypercholesterolemia, familial, 3. An important gene associated with Hyperaldosteronism, Familial, Type Iii is KCNJ5 (Potassium Inwardly Rectifying Channel Subfamily J Member 5). Affiliated tissues include adrenal gland and kidney, and related phenotypes are hypertension and abnormal circulating renin