Hyperostosis

Hyperostosis, also known as hypertrophy of bone, is related to tumoral calcinosis, hyperphosphatemic, familial, 1 and endosteal hyperostosis, autosomal dominant. An important gene associated with Hyperostosis is POLR3GL (RNA Polymerase III Subunit GL), and among its related pathways/superpathways are Signal Transduction and Signaling by Receptor Tyrosine Kinases. The drugs Etanercept and Immunologic Factors have been mentioned in the context of this disorder. Affiliated tissues include bone and bone marrow, and related phenotypes are homeostasis/metabolism and growth/size/body region