Hypersplenism

Hypersplenism, also known as hypersplenia, is related to portal hypertension and aplastic anemia. An important gene associated with Hypersplenism is F2 (Coagulation Factor II, Thrombin), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Heparin, bovine and Nadroparin have been mentioned in the context of this disorder. Affiliated tissues include spleen and bone marrow, and related phenotypes are Reduced mammosphere formation and homeostasis/metabolism