Hypoactive Sexual Desire Disorder, also known as lack or loss of sexual desire, is related to postmenopausal atrophic vaginitis and acne. An important gene associated with Hypoactive Sexual Desire Disorder is HTR1A (5-Hydroxytryptamine Receptor 1A), and among its related pathways/superpathways are Signal Transduction and GPCR downstream signalling. The drugs Progesterone and Progestins have been mentioned in the context of this disorder. Affiliated tissues include brain and breast, and related phenotypes are adipose tissue and behavior/neurological