Hypophosphatemia (VDRR)

Hypophosphatemia, also known as vitamin d-resistant rickets, is related to vitamin d hydroxylation-deficient rickets, type 1a and dominant hypophosphatemia with nephrolithiasis or osteoporosis, and has symptoms including arthralgia and bone pain. An important gene associated with Hypophosphatemia is PHEX (Phosphate Regulating Endopeptidase X-Linked), and among its related pathways/superpathways are Pleural mesothelioma and Negative regulation of FGFR3 signaling. The drugs Iron isomaltoside 1000 and Calcitriol have been mentioned in the context of this disorder. Affiliated tissues include bone and kidney, and related phenotypes are homeostasis/metabolism and renal/urinary system