Hutchinson-Gilford Progeria Syndrome (HGPS)

Alias:
Progeria
Hgps
Hutchinson-Gilford Syndrome
Hutchinson-Gilford Progeria
Hutchinson-Gilford-Progeria Syndrome
Hutchinson Gilford Syndrome
Hutchinson-Gilford Disease
Progeria of Childhood
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Hutchinson-Gilford Progeria Syndrome, also known as progeria, is related to progeroid syndrome and aging. An important gene associated with Hutchinson-Gilford Progeria Syndrome is LMNA (Lamin A/C), and among its related pathways/superpathways are Gene expression (Transcription) and Infectious disease. The drugs Zoledronic acid and Pravastatin have been mentioned in the context of this disorder. Affiliated tissues include skin and bone, and related phenotypes are generalized abnormality of skin and micrognathia
Related ID:

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
AR
AD
Newborn
<1/1000000
54
637
73

Medical Symptom

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Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

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Gene
Function
Score
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
No data available

Disease Model

Category
Name
MGI
Related Gene
Strain of Origin
Publications
No data available

References Literature

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PMID
Journal
Year
IF
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