Histiocytic Sarcoma, also known as malignant histiocytosis, is related to reticulosarcoma and fibrosarcoma of bone. An important gene associated with Histiocytic Sarcoma is CD163 (CD163 Molecule), and among its related pathways/superpathways are Innate Immune System and Cytokine Signaling in Immune system. The drugs Ifosfamide and Doxorubicin have been mentioned in the context of this disorder. Affiliated tissues include thyroid and skin, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance