Hairy Cell Leukemia, also known as hcl-v, is related to refractory hairy cell leukemia and lymphoproliferative syndrome. An important gene associated with Hairy Cell Leukemia is IGHV4-34 (Immunoglobulin Heavy Variable 4-34), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Cladribine and Protective Agents have been mentioned in the context of this disorder. Affiliated tissues include bone marrow and b cells, and related phenotypes are Increased shRNA abundance (Z-score > 2) and immune system