Hairy Cell Leukemia (HCL-V)

Alias:
Hairy Cell Leukemia Variant
Hcl-V
Hairy-Cell Leukaemia Without Mention of Remission
Prolymphocytic Variant of Hairy Cell Leukemia
Leukemic Reticuloendotheliosis Variant
Lre - [leukemic Reticuloendotheliosis]
Leukaemic Reticuloendotheliosis
Prolymphocytic Variant of Hcl
Hairy Cell Leukaemia Variant
Hcl - [hairy Cell Leukaemia]
Hairy-Cell Leukaemia, Nos
Leukemia, Hairy Cell
Leukemia Hairy Cell
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Hairy Cell Leukemia, also known as hcl-v, is related to refractory hairy cell leukemia and lymphoproliferative syndrome. An important gene associated with Hairy Cell Leukemia is IGHV4-34 (Immunoglobulin Heavy Variable 4-34), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Cladribine and Protective Agents have been mentioned in the context of this disorder. Affiliated tissues include bone marrow and b cells, and related phenotypes are Increased shRNA abundance (Z-score > 2) and immune system
Related ID:
MESH:D007943
ICD11:82152208

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
--
Adult
1-9/1000000
28
308
--

Medical Symptom

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Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

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Gene
Function
Score
Mutations
No data available

Related Drugs

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CAS Number
Status
Phase
No data available

Disease Model

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Name
MGI
Related Gene
Strain of Origin
Publications
No data available

References Literature

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PMID
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IF
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