Hearing Loss, Noise-Induced, also known as noise-induced hearing loss, is related to tobacco addiction and age-related hearing loss. An important gene associated with Hearing Loss, Noise-Induced is CDH23 (Cadherin Related 23), and among its related pathways/superpathways are Drug ADME and Glutathione conjugation. The drugs Sorbitol and Orange have been mentioned in the context of this disorder. Affiliated tissues include cortex and brain.