Hurler-Scheie Syndrome (MPS1H/S)

Hurler-Scheie Syndrome, also known as mucopolysaccharidosis type ih/s, is related to scheie syndrome and mononeuropathy of the median nerve, mild, and has symptoms including joint stiffness and thick skin. An important gene associated with Hurler-Scheie Syndrome is IDUA (Alpha-L-Iduronidase), and among its related pathways/superpathways are Infectious disease and Metabolism. The drugs Immunoglobulins and Antibodies have been mentioned in the context of this disorder. Affiliated tissues include bone and eye, and related phenotypes are coarse facial features and splenomegaly