Hereditary Lymphedema I (PCL)

Hereditary Lymphedema I, also known as lymphedema, is related to hypotrichosis-lymphedema-telangiectasia-renal defect syndrome and lymphatic malformation 1, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Hereditary Lymphedema I is FLT4 (Fms Related Receptor Tyrosine Kinase 4), and among its related pathways/superpathways are Phospholipase-C Pathway and p70S6K Signaling. The drugs Fentanyl and Propofol have been mentioned in the context of this disorder. Affiliated tissues include Heart, lymph node and breast, and related phenotypes are growth/size/body region and homeostasis/metabolism