Hereditary Late-Onset Parkinson Disease (LOPD)

Hereditary Late-Onset Parkinson Disease, also known as autosomal dominant late-onset parkinson disease, is related to glucosidase acid-1,4-alpha deficiency and glycogen storage disease ii. An important gene associated with Hereditary Late-Onset Parkinson Disease is DNAJC13 (DnaJ Heat Shock Protein Family (Hsp40) Member C13), and among its related pathways/superpathways are Parkinson's disease pathway and Involvement of -secretase in neurodegenerative diseases. The drugs Temsirolimus and Acetaminophen have been mentioned in the context of this disorder. Affiliated tissues include tongue and subthalamic nucleus, and related phenotypes are parkinsonism and diplopia