Hereditary Breast Cancer

Hereditary Breast Cancer, also known as hereditary breast carcinoma, is related to breast-ovarian cancer, familial 2 and ovarian cancer 1. An important gene associated with Hereditary Breast Cancer is BRCA2 (BRCA2 DNA Repair Associated), and among its related pathways/superpathways are Homology Directed Repair and Homologous DNA Pairing and Strand Exchange. The drugs Selenium and Trace Elements have been mentioned in the context of this disorder. Affiliated tissues include breast and lymph node, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and Decreased homologous recombination repair frequency