Hereditary Cerebral Amyloid Angiopathy

Alias:
Cerebral Amyloid Angiopathy, Hereditary
Cerebral Amyloid Angiopathy, Familial
Hereditary Cerebral Hemorrhage with Amyloidosis-Icelandic Type
Hereditary Cerebral Hemorrhage with Amyloidosis-Dutch Type
Autosomal Dominant Cerebrovascular Amyloidosis
Cerebral Amyloid Angiopathy, Genetic
Familial Cerebral Amyloid Angiopathy
Cerebral Amyloid Angiopathy Familial
Caa, Familial
Hchwa-D
Hchwa-I
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Hereditary Cerebral Amyloid Angiopathy, also known as cerebral amyloid angiopathy, hereditary, is related to cerebral amyloid angiopathy, cst3-related and cerebral amyloid angiopathy, app-related. An important gene associated with Hereditary Cerebral Amyloid Angiopathy is APP (Amyloid Beta Precursor Protein), and among its related pathways/superpathways are Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) and Neuroscience. The drugs Minocycline and Anti-Bacterial Agents have been mentioned in the context of this disorder. Affiliated tissues include brain and smooth muscle, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Upregulation of Wnt/beta-catenin pathway after WNT3A stimulation
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Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
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Unknown
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3
57
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Medical Symptom

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Gene & Mutation

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Disease Model

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MGI
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Publications
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References Literature

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