Hepatic Veno-Occlusive Disease

Hepatic Veno-Occlusive Disease, also known as sinusoidal obstruction syndrome, is related to pulmonary edema and pulmonary hypertension. An important gene associated with Hepatic Veno-Occlusive Disease is PLAT (Plasminogen Activator, Tissue Type), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Diseases of hemostasis. The drugs Inotuzumab ozogamicin and Immunologic Factors have been mentioned in the context of this disorder. Affiliated tissues include liver and bone marrow, and related phenotypes are hepatomegaly and renal insufficiency