Hepatorenal Syndrome, also known as hrf - [hepatorenal failure], is related to peritonitis and alcoholic hepatitis. An important gene associated with Hepatorenal Syndrome is ALB (Albumin), and among its related pathways/superpathways are Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) and Aquaporin-mediated transport. The drugs Norepinephrine and Norfloxacin have been mentioned in the context of this disorder. Affiliated tissues include liver and kidney, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and homeostasis/metabolism