Heme Oxygenase 1 Deficiency, also known as heme oxygenase-1 deficiency, is related to thrombocytosis and hemolytic anemia. An important gene associated with Heme Oxygenase 1 Deficiency is HMOX1 (Heme Oxygenase 1). Affiliated tissues include endothelial and bone marrow, and related phenotypes are hypertension and hepatomegaly